巴西专利BR112012008010A2 synergistic fungicidal mixtures for fungal control in cereals

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专利摘要:
SYNERGIC FUNGICID MIXTURES FOR Fungal Control in Grains.The present invention relates to a composition containing the fungicidally effective quality of a compound of formula IV and at least one fungicide selected from the group consisting of epoxiconazole, protioconazole, azoxystrobin, piraclostrobin, pentiopirad, isopirazam, bixafen, boscalid, procloraz, and chlorothalonil provides synergistic control of selected fungi.
公开号:BR112012008010A2
申请号:R112012008010-5
申请日:2010-10-06
公开日:2020-08-25
发明作者:W. John OWEN；Chenglin Yao
申请人:Dow Agrosciences Llc；
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专利说明:

Descriptive Report of the Invention Patent for "SYNERGIC FUNGICID MIXTURES 'FOR THE Fungal Control in Cereals. AIS". Cross Reference with Related Applications This application claims the benefit of U.S. Provisional Patent Application no. 61/249479, filed on October 7, 2009, which is expressly incorporated by reference here.
Field of the Invention The present invention relates to a synergistic fungal composition containing (a) a compound of the formula |, II, III, IV or V and (b) at least "a fungicide selected from the group consisting of epoxiconazole, protioco- 'nazol, azoxystrobin, piraclostrobin, pentiopirad, isopirazam, bixafen, boscalid, ”prochloraz, and chlorothalonil.
Background of the Invention Fungicides are compounds, of natural or synthetic origin, that act to protect plants against damage caused by fungi.
Current methods of agriculture rely heavily on the use of fungicides.
In fact, some crops cannot be developed lately without the use of fungicides.
Using fungicides allows a grower to increase yield and crop quality, and consequently to increase crop value.
In most situations, the increase in harvest value is at least three times the cost of using the fungicide.
However, no fungicide is useful in all situations and repeated use of a single fungicide often leads to the development of resistance to that and related fungicides.
Consequently, research is being conducted to produce fungicides and combinations of fungicides that are protective, that perform better, that require lower dosages, that are easier to use, and that cost less.
Synergism occurs when the cavity of two or more compounds exceeds the activities of the compounds when used alone.
Summary of the Invention It is an objective of the invention to provide synergistic compositions
comprising fungal compounds. It is another objective of the invention to provide processes that use these synergistic compositions. Synergistic compositions are capable of preventing or curing, or both, diseases caused by fungi of the classes Ascomycetes and Basidiomycetes. In addition, synergistic compositions have improved efficacy against Ascomycete Basidiomycete pathogens, including leaf spot and brown wheat rust. According to the invention, synergistic compositions are provided together with methods for their use. Detailed Description of the Invention The present invention relates to a synergistic fungicidal mixture 'comprising a fungicidally effective amount of (a) a compound' of the formula |, Il, Ill, IV or V, and (b) at least one fungicide selected from the group consisting of epoxiconazole, protioconazole, azoxystrobin, piraclostrobin, pentiopirad, isopyrazam, bixafen, boscalid, prochloraz and chlorothalonil. WA
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V | Azoxystrobin is the common name nara (aE) -2-8- (2-cyanophenoxy) A-
methyl pyrimidinyl-a- (methoxymethylene) benzeneacetate. Its' fungal activity is described in the Pesticide Manual, Fourth edition, 2006. Azoxistrobin. controls a variety of pathogens at application rates between 100 and 375 grams / hectare (g / ha).
Bixafen is the common name for N- (3 ', 4'-dichloro-5-fluoro [1,1 "- biphenyl] -2-iI) -3- (difluoromethyl) -1-methyl-1H-pyrazole-4- carboxamide Bixafen controls a variety of pathogens such as Sepforia tritici and rust.
Boscalid is the common name for 2-chloro-N- (4'-chlorobiphenyl-2- i) nicotinamide. Its fungal activity is described in the Pesticide Manual, 5th edition, 2009. Boscalid provides powder control, Alternaria, Botrytis, Sclero- "tinia, Mycoshpaerella and Monilinia in fruit, peat, cereals, rapeseed, peanuts and" potatoes. BR Chlorothalonil is the common name for tetraciorisophthalonitrile. Its fungal activity is described in The Pesticide Manual, Fifth edition, 2009.
—Chlorotalonil controls a wide variety of pathogens at rates of application between 1000 to 2500 g / ha.
Epoxiconazole is the common name for rel-1 - [[(2R, 3S) -3- (2-chlorophenyl) -2- (4-fluorophenyl) oxiranyl | methyl] -1H-1,2,4-triazole. Its fungal activity is described in The Pesticide Manual, Fourth edition, 2006. Epoxiconazole provides broad-spectrum fungal control, with preventive or curative action, of diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes in cereals and sugar beet.
Isopyrazam is the common name for 3- (difluoromethyl) -1-methyl-N- [1,2,3 4-tetrahydro-9- (1-methylethyl) - 1,4-methanonatphthalene-5-yl] -1H-pyrazole -4- carboxamide. Its fungal activity is described in The Pesticide Manual, Fifth edition, 2009. Isopirazam provides control of Septoria and rust in wheat, as well as Ramularia in barley.
Pentiopirad is the common name for N- [2- (1,3-dimethylbutyl) -3-thienyl] - 1-methyl-3- (trifluoromethyl) -1H-pyrazol-4-carboxamide. Its fungal activity is described in The Pesticide Manual, Fourth Edition, 2006. Pentiopirad provides control of Rhizoctonia and rust diseases, as well as gray mold, powdery mildew and apple scab.
Prochloraz is the common name for N-propyl-N- [2,4,6- 'trichlorophenoxy) ethillimidazole-1-carboxamide. Its fungal activity is described. in The Pesticide Manual, Fifth Edition, 2009. Procloraz provides control against a wide variety of pathogens at rates of application between 400 aG600giaha.
Protioconazole is the common name for 2- [2- (1-chlorocyclopropyl) -3- (2-chlorophenyl) -2-hydroxypropyl] -1,2-dihydro-3H-1,2,4-triazole-3-thione. Its fungal activity is described in The Pesticide Manual, Fourth edition, 2006. Protoconconazole is used to control diseases such as eye spots, early Fusarium rust, leaf spot, rust and powdery mildew by application. leaf in wheat, barley and other crops. 7 Piraclostrobin is the common name for methyl [2 - [[[1- (4-chlorophenyl) -1H-pyrazol-3-ylJoxymethylJphenyl | methoxycarbamate. Its fungal activity is: described in The Pesticide Manual, Fourth edition, 2006. Piraclostrobin controls major plant pathogens, such as Septoria tritici, Puccinia Spp., Drechslera tritici-repentis and Pirenophora teres in cereals.
In the composition of the invention, the weight ratio of compounds of the formula | -V to epoxiconazole in which the fungal effect is synergistic is within the range of about 1:10 to about 10: 1. The weight ratio of compounds of the formula | -V to protioconazole in which the fungal effect is synergistic is within the range of about 1:10 to about 10: 1. The weight ratio of compounds of the formula | -V to azoxystrobin in which the fungal effect is synergistic is within the range of about 1:10 to about 10: 1. The weight ratio of compounds of the formula | -V to piraclostrobin in which the fungal effect is synergistic is within the range of about 1:10 to about 10: 1. The weight ratio of compounds of the formula | -V to pentiopyrad in which the fungal effect is synergistic is within the range of about 1:10 to about 10: 1. The weight ratio of the compound of the formula | for isopirazam in which the fungal effect is synergistic it is within the range of about 1: 10 to about 10: 1. The weight ratio of the compound of the formula | for bixafen in which the fungal effect is synergistic it is within the range between about 1:10 and about 10: 1. The weight ratio of the compounds in the
mule | -V for boscalid in which the fungal effect is synergistic is within the range of between about 1:10 and about 10: 1. The weight ratio of the compos-. of the | -V formula for prochloraz in which the fungal effect is synergistic is within the range of about 1:10 to about 10: 1. The weight ratio of compounds of the formula | -V to chlorothalonil in which the fungal effect is synergistic is within the range of about 1:50 to 1: 1.
The rate at which the synergistic composition is applied will depend on the particular type of fungus to be controlled, the degree of control required and the time and method of application. In general, the composition of the invention can be applied at an application rate of between about 65 grams per hectare (g / ha) and about 2300 g / ha based on the total amount of active ingredients in the composition. Epoxiconazole is applied at a rate between about 30 g / ha and about 125 g / ha and the compound of the formula | -V is applied at: a rate between about 35 g / ha and about 300 g / ha. Protioconazole is applied at a rate between about 50 g / ha and about 200 g / ha and the compound of the formula | -V is applied at a rate between about 35 g / ha and about 300 g / ha. Azoxystrobin is applied at a rate between about 50 g / ha and about 250 g / ha and the compound of the formula | -V is applied at a rate between about 35 g / ha and about 300 g / ha. Piraclostrobin is applied at a rate between about 50 g / ha and about 250 g / ha and the compound of the formula | -V is applied at a rate between about 35 g / ha and about 300 g / ha. Pentiopirad is applied at a rate between about 50 g / ha and about 300 g / ha and the compound of the formula | -V is applied at a rate between about 35 g / ha and about 300 g / ha. Isopirazam is applied at a rate between about 30 g / ha and about 125 g / ha and the compound of the formula | is applied at a rate between about 35 g / ha and about 300 g / ha Bixafen is applied at a rate between about 30 g / ha and about 125 g / ha and the compound of the formula | it is applied at a rate between about 35 g / ha and about 300 g / ha. Boscalid is applied at a rate between about 50 g / ha and about 350 g / ha and the compound of the formula | -V is applied at a rate between about 35 g / ha and about 300 g / ha. Prochloraz is applied at a rate between about 50 g / ha and about 450 g / ha and the compound of the formula | -V is applied at a rate between about 35 g / ha and about
300 g / ha. Chlorothalonil is applied at a rate between about 100 g / ha and about 2000 g / ha and the compound of the formula | -V is applied at a rate between, about 35 g / ha and about 300 g / ha there is. The components of the synergistic mixture of the present invention can be applied either separately or as part of a multi-part fungal system.
The synergistic blend of the present invention can be applied in combination with one or more other fungicides to control a wider variety of undesirable diseases. When used in combination with other fungicide (s), the compounds currently claimed may be formulated with other fungicide (s), mixed in the tank with the other fungicide (s) or applied sequentially with other fungicide (s). Such: other fungicides may include 2- (thiocyanatomethylthio) -benzothiazole, 2-phenylphenol, 8-hydroxyquinoline sulfate, ametoctradin, amisulbrom, antimycin, Amelomyces quisqualis, azaconazole, azoxystrobin, Bacillus subtilis, bacillus subtilis, benign QOST7 benomile, bentiavalicarb-isopropyl, benzylaminobenzene sulfonate salt (BABS), bicarbonates, biphenyl, bismertiazole, bitertanol, bixafen, blasticidin-S, borax, Bordeaux mixture, boscalid, bro- muconazole, cappyride, cappyride, polysulfide, polysulfide, polysulfate , carbendazim, carboxin, carpropamid, carvone, clazafenone, chloroneb, chlorothalonil, clozolinate, Coniothyrium minitans, copper hydroxide, copper octanoate, copper oxychloride, copper (tribasic), cuprous oxide, ciazofamid, ciflufenyl, ciflufenid, ciflufenid cyproconazole, ciprodinil, dazomet, debacarb, diamonium ethylbenz- (dithiocarbamate), diclofluanid, dichlorophen, diclocimet, diclomezine, dichloran, dietofencarb, diphenoconazole, difenzo ion quat, diflume-torim, dimetomorph, dimoxystrobin, diniconazole, diniconazole-M, dinobuton, dinocap, diphenylamine, dithianon, dodemorf, dodemorf acetate, dodine, dodine-free base, edifenfos, enestrobin, enestroburin, ethanol, epoxyl, epoxy, epoxy , famoxadone, fenamidone, fenarimol, fenbuconazole, fenuramam, fenexamid, fenoxanil, fenpiclonil, fenpropidina, fenpropimorf, fenpi- razamine, fentina, fentina acetate, fentina hydroxide, ferbam, ferimzo-, fluazinam, fludiofamily , fluopyram, fluoroimide, fluoro- and xastrobin, fluquinconazole, flusilazole, flusulfamide, flutianyl, flutolanyl, flutria-] fol, fluxpyroxad, folpet, formaldehyde, fosetil, fosetil-aluminum, fuberidazo !,. furalaxil, furametpir, guazatin, acetates of guazatin, GY-81, hexachloro-benzene, hexaconazole, himexazole, imazalil, imazalyl sulfate, imibenco-nazol, iminoctadine, iminoctadine triacetate, iminoctadine, iodine, ipodazole, trisazidate iprobenfos, iprodione, iprovalicarb, isopropiolan, isopirazam, isothyanil, casugamycin, ca-sugamycin hydrochloride, cresoxim-methyl, laminarine, mancopper, mancozeb, mandipro-pamid, maneb, mefenoxam, meprepine, meprepine, mepanipyrim, mepanipirim, mepanipir, mepanippimim, mepanipir, mepanipir, mepanipir, mepanipir, mepanipir, mepanipir. mercuric chloride, mercuric oxide, metalaxyl, metalaxyl-M, metam, metam-. ammonium, metam-potassium, metam-sodium, metconazole, metasulfocarb, methyl iodide 7, methyl isothiocyanate, metiam, metominostrobin, metrafenone, 'mildiomycin, miclobutanil, nabam, nitrotal-isopropyl, nuarimol, octilinone, acid, ouraceous, acid; fatty acids), orisastrobin, oxadixyl, oxin-copper, ox- —poconazolfumarate, oxycarboxin, pefurazoate, penconazole, pencycuron, penflufen, pentachlorophenol, pentachlorophenyl laurate, pentiopirad acetate, phenyl- mercury, polysulfide, phosphonic acid, phosphonic acid, phosphonic acid , polyoxins, polyoxorim, potassium bicarbonate, hydroxyquinoline potassium sulphate, probe-nazol, prochloraz, procymidone, propamocarb, propamocarb hydrochloride, propiconazole, propineb, proquinazid, protioconazole, pyraclostrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin, pyrethoxytrobin. pyributicarb, pirifenox, pyrimethanine, pyrophenone, piroquilon, quinoclamine, quinoxifen, quintozene, Reynoutria sachalinensis extract, silkxane, siltiofam, simeconazole, 2 -sodium phenylphenoxide, sodium bicarbonate, sodium pentachlorophenoxide, spiroxamine, sulfur, SYP-Z048, tar oils, tebuconazole, tebufloquin, tecnazene, tetraconazole, thiabendazole, tifluzamide, thiophanate-methyl, tiram, tiad, tiad, tiad, tiad, tiad , tolylfluanid, triadimefon, triadimenol, triazoxide, tricyclazole, tride-morph, trifloxystrobin, triflumizole, triforin, triticonazole, validamycin, valifenalate, valifenal, vinclozolin, zineb, ziram, zoxamide, Phyloxy, spide, Candida, Candida, Phyllisium, spina Streptomyces griseoviri- dis, Trichoderma spp., (RS) -N- (3,5-dichlorophenyl) -2- (methoxymethyl) -succinimide, 1,2-dichloropropane, - 1,3-dichloro-1,1 hydrate, 3,3-tetrafluoroacetone, 1-
chloro-2 4-dinitronaftalene, 1-chloro-2-nitropropane, 2- (2-heptadecyl-2-] imidazolin-1-yl) ethanol, 2,3-dihydro-5-phenyl-1,4-dithiine 1,1,4,4-tetraoxide, 2-methoxyethylmercury acetate, 2-methoxyethylmercury chloride, 2-methoxyethylmercury silicate, 3- (4-chlorophenyl) -5-methylrodanine, 4- (2-nitroprop-1- enyl) phenyl thiocyanate, ampropylphos, anilazine, azithiram, barium polysulfide, Bayer 32394, benodanil, benquinox, bentaluron, benzamacrila; benzamacryl-isobutyl, benzamorf, binapacryl, bis (methylmercury) sulphate, bis (tributyltin) oxide, butiobate, cadmium calcium copper zinc chromate sulphate, carbamorf, ECSC, clobentiazone, chloraniformethan, chlorphenol, chloroquine, chloroquine ) copper, copper zinc chromate, cufraneb, "cupric hydrazinium sulfate, cuprobam, cilafuramid, cipendazole, ciprofuram," decafentin, diclone, diclozoline, diclobutrazol, dimethyrimol, dinocton, dinosul-. fon, dinoterbon, dipiritiona, ditalimfos, dodicin, drazoxolon, EBP, ESBP, eta-conazole, etem, ethirim, phenaminosulf, fenapanila, fenitropan, fluotrimazol, fur-carbanil, furconazol, furconazol-cis, furmecicilox, furmecicilox, furmecicilox, furofecicolox, furofecicilox, furofecicilox, fulvin, halacrinate, Hercules 3944, hexylthiophos, ICIA0858, isopamphos, isovaleidione, mebenilla, mecarbinzid, metazoxolon, metfuroxam, methylmercury diciandiamide, metsulfovax, milneb, hydrochloride-N-hydrochloride-N-chloro-hydrochloride, myclozolin; -3-nitrophenylitaconimide, - natamycin, - N-etimercurium-4-toluenesulfonanilide, nickel bis (dimethyldithiocarbamate), OCH, phenylmercury dimethyldithiocarbamate, phenylmercury nitrate, phosdi- phen, protiocarb; protiocarb hydrochloride, piracarbolid, pyridinitrile, pyroxychlor, pyroxifur, quinacetol; quinacetol sulfate, quinazamid, quinconazole, rabenzazazole, salicylanilide, SSF-109, sultropen, tecoram, thiadifluor, ticiofen, thioclorphenphim, thiophanate, thioquinox, thioximid, triamiphos, triarimol, triazbutyl, triazbutyl, triazbutyl
mida, urbacid, zarilamid, and any combinations thereof.
The compositions of the present invention are preferably applied in the form of a formulation comprising a composition of (a) a compound of the formula | and (b) at least one fungicide selected from the group consisting of epoxiconazole, protioconazole, azoxystrobin, piraclostrobin, pentiopirad, isopyrazam, bixafen, boscalid, prochloraz, and chlorothalonil,
along with a pathologically acceptable vehicle.
Concentrated formulations can be dispersed in water or another liquid, for application or formulations can be of the dust or granular type, which can then be applied without further treatment. The formulations are prepared according to procedures that are conventional in the agricultural chemistry technique, but which are new and important because of the presence of a synergistic composition there.
The formulations that are applied most often are aqueous suspensions or emulsions. Or such water-soluble, water-suspendable or emulsifiable formulations are solid, usually known as wettable powders, or liquids, usually known as emulsifiable concentrates, aqueous suspensions or suspension concentrates. The present invention contemplates all vehicles by which the compositions. Synergistic reactions can be formulated for supply and use as a fungicide.
As will be readily appreciated, any material to which these synergistic compositions can be used, provided that they provide the desired utility without significant interference with the activity of these synergistic compositions as antifungal agents.
Wettable powders, which can be compacted to form water-dispersible granules, comprise an intimate blend of the synergistic composition, an agriculturally acceptable carrier and surfactants. The concentration of the synergistic composition in the wettable powder is usually about 10% to about 90% by weight, more preferably about 25% to about 75% by weight, based on the total weight of the formulation. In the preparation of wettable powder formulations, the synergistic composition can be combined with any of the finely divided solids, such as pyrophyllite, talc, chalk, plaster, Fuller's earth, bentonite, atapulgite, starch, casein, gluten, clays. montmorillonite, diatomaceous earth, purified silicates or the like. In such operations, the finely divided vehicle is ground or mixed with the synergistic composition in a volatile organic solvent. Effective surfactants, comprising from about 0.5% to about 10% by weight of wettable powder, include sulfonated lignins, naphthalenesuflphonates, alkylbenzene-
our sulfonates, alkyl sulfates, and non-ionic surfactants, such as ethylene oxide addition products for alkyl phenols. Emulsifiable concentrates of the synergistic composition comprise a convenient concentration, such as from about 10% to about 50% by weight, in a suitable liquid, based on the total weight of the emulsifiable concentrate formulation. The components of the synergistic compositions, together or separately, are dissolved in a vehicle, which is either a water-miscible solvent or a mixture of water-immiscible organic solvents, and emulsifiers. The concentrates can be diluted with water and oil to form spray mixtures in the form of oil-in-water emulsions. Useful organic solvents include aromatics, especially high-boiling naphthalene and olefinic portions of oil such as heavy aromatic naphtha. Other organic solvents can also be used, such as, for example, terpenic solvents, including rosin derivatives, aliphatic ketones, such as cyclohexanone, and complex alcohols, such as 2-ethoxyethanol.
Emulsifiers that can be advantageously employed here can readily be determined by those skilled in the art and include various nonionic, anionic, cationic and amphoteric emulsifiers, or a combination of two or more emulsifiers. Examples of non-ionic emulsifiers useful in the preparation of emulsifiable concentrates include polyalkylene glycol ethers and condensation products of alkyl and aryl phenols, aliphatic alcohols, aliphatic amines or fatty acids with ethylene oxide, propylene oxide such as alkyl phenols ethoxylated carboxylic esters solubilized with polyol or polyoxyalkylene. Cationic emulsifiers include quaternary ammonium compounds and grease amine salts. Anionic emulsifiers include oil-soluble salts (eg calcium) of alkylaryl sulfonic acids, oil-soluble salts or polyglycol ethers! sulphates and appropriate salts of polyglycether! phosphated. Representative organic liquids that can be employed in the preparation of the emulsifiable concentrates of the present invention are aromatic liquids such as xylene, propyl benzene fraction, or mixed naphthalene fractions, mineral oils, substituted aromatic organic liquids such as dioctyl phthalate, kerosene, dialkyl amides of various fatty acids. compounds, particularly the dimethyl amides of fatty glycols and glycol derivatives such as e-n-butyl ether, ethyl ether or diethylene glycol methyl ether, triethylene glycol methyl ether. Mixtures of two or more organic liquids are also often used to prepare the emulsifiable concentrate. Preferred organic liquids are xylene and propyl benzene fraction, with xylene being more preferred. Surfactant dispersing agents are usually employed in liquid formulations and in the amount of from 0.1 to 20 weight percent of the dispersion agent's combined weight with the synergistic compositions. The formulations may also contain other compatible additives, for example: plant growth regulators and other biologically active compounds used in agriculture.
Aqueous suspensions comprise suspensions of one or more water-insoluble compounds, dispersed in an aqueous vehicle at a concentration in the range of about 5% to about 70% by weight, based on the total weight of the aqueous suspension formulation. Suspensions are prepared by finely grinding the components of the synergistic combination or between separately, and vigorously mixing the ground material in a vehicle consisting of water and surfactants chosen from the same types discussed above. Other ingredients, such as inorganic salts and synthetic or natural gums, can also be added to increase the density and viscosity of the aqueous vehicle. It is often more effective for grinding and mixing at the same time by preparing the aqueous mixture and homogenizing it in an implement such as a sand mill, ball mill or piston-type homogenizer.
The synergistic composition can also be applied as a granular formulation, which is particularly useful for applications to the soil.
—Granular formulations usually contain from about 0.5% to about 10% by weight of the compounds, based on the total weight of the granular formulation, dispersed in a vehicle that consists entirely or in large part of coarsely divided atapulgite, bentonite , diatomite, clay, or a similar cheap substance. Such formulations are usually prepared by dissolving. tion of the synergistic composition in a suitable solvent and application of it to a granular vehicle that has been preformed to give the appropriate particle size, in the range of about 0.5 to about 3 mm. Such formulations can also be prepared by producing the mass or paste of the vehicle and the synergistic composition, and grinding and drying to obtain the desired granular particle.
Dusts containing the synergistic composition are simply prepared by intimately mixing the synergistic composition in powder form "with a powdered agricultural vehicle, such as, for example, kaolin, clay, ground volcanic rock, esimilar. Dusts can suitably contain from about 1% to about 10% by weight of the synergistic composition / vehicle combination.
The formulations may contain agriculturally acceptable surfactants to increase deposition, wetting and penetration of the synergistic composition on the target crop and organism. These auxiliary surfactants can optionally be used as a component of the formulation or as a tank mixture. The amount of auxiliary surfactant will vary from 0.01 percent to 1.0 percent volume / volume (v / v) based on a volume of water spray, preferably from 0.05 to 0.5 percent. Suitable auxiliary surfactants include ethoxylated nonyl phenols, ethoxylated synthetic or natural alcohols, salts of sulfosuccinic esters or acids, ethoxylated organo silicones, ethoxylated fatty acid amines and detentative combinations with vegetable or mineral oils.
The formulations can optionally include combinations that can comprise at least 1% by weight of one or more of the synergistic compositions with another pesticidal compound. Such additional pesticide compounds may be fungicides, insecticides, nematocides, miticides, —arthropodicides, bactericides or combinations thereof that are compatible with the synergistic compositions of the present invention in the medium selected for application, and not antagonistic to the activity of the present compounds.
posts. Correspondingly, in such embodiments the other compound 'pesticide is employed as a supplemental toxicant for the same or for. a different pesticide use. The pesticidal compound and the synergistic composition can in general be mixed together in a weight ratio of from 1: 100 to 1001.
The present invention includes within its scope methods for the control or prevention of fungal attacks. These methods include application to the fungus site, or to a location where infestation should be avoided (for example, application to wheat or barley plants), the fungicidally effective amount of the synergistic composition. The synergistic composition is suitable for the treatment of various plants at fungal levels, while exhibiting low phytotoxicity. The synergistic composition is useful in a B. protective or eradicating form. The synergistic composition is applied by any of a variety of known techniques, or as the synergistic composition or as one comprising the synergistic composition. For example, synergistic compositions can be applied to the roots, seeds or leaves of plants to control various fungi, without damaging the commercial value of plants. The synergistic composition is applied in the form of any of the types of formulation in general used, for example, as solutions, dust, wettable powders, flowable concentrates, or emulsifiable concentrates. These materials are conventionally applied in several known ways.
The synergistic composition has been shown to have a significant fungal effect, particularly for agricultural use. The synergistic composition is particularly effective for use with agricultural crops and horticultural plants, or with wood, paint, leather, carpet backing.
In particular, the synergistic composition is effective in controlling a variety of unwanted fungi that infect useful plant crops. The synergistic composition can be used against a variety of Ascomycetee Basidiomycete fungi, including for example, the following representative fungal species: wheat brown rust (Puccinia recondita; Bayer code PUCCRT); wheat strip rust (Puccinia striiformis; Bayer code PUCCST); stain on the wheat leaf (Mycosphaerella graminicola;] anamorf: Septoria tritici, Bayer SEPTTR code); glume stain of. wheat (Leptosphaeria nodorum; Bayer LEPTNO code; anamorf: Stagnospora nodorum); brown spot of barley (Cochliobolus sativum; code Bayer COCHSA; anamorph: Helminthosporium sativum); sugar beet leaf spot (Cercospora beticola; Bayer code CERC-BE); peanut leaf spot (Mycosphaerella arachidis; Bahy MYCOAR code; anamorph: Cercospora arachidicola); cucumber anthracnose (Glomerella lagenarium; anamorph: Colletotrichum lagenarium; code of the BELLERCOLLLA) and banana black sigatoka disease (Mycosphaerella fijien- 7 sis; code of the BAYER MYCOFI). It will be understood by those in the art that: the effectiveness of synergistic compositions by one or more of the exposed fungi. above establishes the general utility of synergistic compositions as fungicides.
Synergistic compositions have a wide range of effectiveness as a fungicide. The exact amount of the synergistic composition to be applied is dependent not only on the relative quantities of the components, but also on the particular desired action, the fungal species to be controlled, and the stage of its growth, as well as the part of the plant or another product to be put in contact with a synergistic composition. Thus, formulations containing the synergistic composition may not be equally effective at similar concentrations or against the same fungal species.
Synergistic compositions are effective in use with plants in a phytologically acceptable and disease-inhibiting amount. The term "phytologically acceptable amount and disease inhibition" refers to an amount of the synergistic composition that kills or inhibits the plant disease for which control is desired, but is not significantly toxic to the plant. The exact concentration of the required synergistic composition varies with the fungal disease to be controlled, the type of formulation used, the method of application, the particular plant species, climatic conditions, similar.
The present compositions can be applied to fungi or their location by the use of conventional soil sprinklers, granule applicators, and by other conventional means known to those skilled in the art. unique.
The following examples are provided to further illustrate the invention.
They are not intended to be construed as limiting the invention.
Examples Evaluation of protective and curative activity of fungicide mixtures versus wheat leaf spot (Mycosphaerella graminicola; anamorph: Septoria tritici, Bayer code: SEPTTR) 7 Wheat plants (variety Yuma) were developed from ' seed in a greenhouse in plastic pots with a surface area. 27.5 cm squared (cm ) containing 50% mineral soil / 50% soil less Metro mix, with 8-12 seedlings per pot.
The plants were used for testing when the first leaf was fully grown, which typically took 7 to 8 days after planting.
Test plants were inoculated with an aqueous spore suspension of Septoria tritici either 3 days before (3-day curative test) or 1 day after fungicide treatments (1-day protective test). After inoculation, the plants were kept at 100% relative humidity (one day in a dark condensation chamber followed by two days in a lighted mist chamber) to allow spores to germinate and infect the leaf.
The plants were then transferred to a study for the disease to develop.
Evaluation of curative activity of fungicide mixtures versus brown wheat rust (Puccinia recondita; Bayer code: PUCCRT) Yuma wheat seeds were developed as described above, and were inoculated with a 3-day aqueous suspension of Pucocinia spore before or 1 day after fungicide treatment.
After inoculation, plants were kept at 100% relative humidity - for 24 hours in a dark condensation room to allow spores to germinate and infect plants.
The plants were then transferred to a greenhouse for the disease to develop.
Treatments consisted of compound fungicides |, II, III, IV, V,, epoxiconazole, protioconazole, azoxystrobin, piraclostrobin, pentiopirad, bosca-. lid, prochloraz, and chlorothalonil, either individually or as a mixture of two media with | -V compounds. For compound |, isopirazam and bixafen were also included in the studies. Technical grade materials were dissolved in acetone to form stock solutions, which were then used to perform dilutions in acetone or for each individual fungicidal component or for mixtures of two media. Desired fungicide rates were obtained after mixing dilutions with 9 volumes of water containing 110 parts per million (ppm) Triton X-100. Twenty milliliter 7 (mL) of fungicide solutions were applied over 12 pots of plants' using an automated spray booth, which used two nozzles. spray gun 6218-1 / 4 JAUPM operating a set of 137.89 KPa (20 pounds per inch squared (psi)) at opposite angles to cover both surfaces of the sheet. All sprayed plants were allowed to air dry for further handling. Control plants are sprayed in the same way with the blank solvent. When disease fully developed in control plants, levels of infection were assessed in plants visually treated and rated on a scale of 0 to 100 percent. Percentage of disease control was then calculated using the disease ratio in the treated plants with respect to control plants. Colby's equation was used to determine the expected fungal effects of the mixtures. (See Colby, S. R. Calculation of the synergistic and antagonistic response of herbicide combinations. Weeds 1967, 15, 20-
22.) The following reaction was used to calculate the expected activity of mixtures containing two active ingredients, A and B: Expected = A + B - (A x B / 100) A = observed effectiveness of active component A at the same concentration used than used in the mixture; B = observed effectiveness of active component B in the same context
centering used than used in the mixture. 'Representative synergistic interactions are presented in the se-. following Tables 1-12. % of DC Obs = Percentage of disease control observed% of DC Exp = Percentage of disease control expected Synergism factor =% of DC Obs /% of DC Exp Table 1: Synergistic interactions of compound | and other fungicides in the Septoria tritici (SEPTTR) 3-day dressing (3DC) tests | reasm | Doom | Doi | sregermo Taxappm | DCobs | DCexp | synergism OO ESSES [o Dn | 16 | I + epoxiconazole 0.4 + 0.1 71 43 1.64 ESSA we went | | | 20. I + epoxiconazole 0.15 + 0.13 97 48 2.02
ECPENPPIPINNRTA I + protioconazo! L 0.4 +25 72 1.38 Compound [note - | wing | oo It's 6th | 1% Lspratccams - | oasis | so is 7 sound | I + protioconazole 0.45 + 0.6 7
ESSNPPIPITIRTA I + azoxystrobin 6.25 +0.4 100 1.12 nap - | rasizas | 00 | if | xo I + azoxystrobin 1.35 + 2.25 83 1.19 Qnsrasasmam Compound -) orsos | sa | so I n + piraclostrobin 0.1 +04 92 1.15 [Compound rpentiopirad | 62601 | 86 | so | in [Mrisopirazam Compound | 62501 | 88 | 8 | 11 | [Fisopirazam compound | 0.456,25 | 68 | 56 | 128 | [Irisopyrazam compound | 016.25 | 86 | 57 | 180
Table 2: Synergistic interactions of compound | and other Fungicides in the protective 1-day (1DP) SEPTTR tests E rnagm | Das | Dai sregeno | Ppm rate | DC obs | DC exp | synergism [Compound repoxicanazel [0170025] 85 | 55 | 153 | | Irprotioconazole Compound | ot 1.56 | 94 | 70 | 13 [Irprofionazole compound | 015502 | 46 | 15 | aor | [Razoxisirapim compound [otr156] 91 | 66 | 138 | [Irazoxisiraoim compound | other | ão | 6 | 13 - irpraciostobin compound | 01501 [so | sa | fly | - rrpracostobin compound [005008 | 68 | ão | 227 | - Jeomposioirpentoprad | ogrog | 6 | oo | to | [Compound risopiraram - [015013 | 49 | 9 | 568 | [Chloroalonta compound | bones | 16 | & | 18 | Table 3: Synergistic interactions of compound | and other Fungicides in 3DC tests Puccinia recondita (PUCCRT) ie É | E and DC DC Factor
Ppm rate exp exp | synergism
[Irepoxicanazal compound | oa + ot | 100 | 8 | 115 |
[Mepoxicanazole compound | 0101 | 100 | 82 | 122 |
[Irazoxistoim compound | 04 + 04 | so | if | 107 |
[Irazoxisabin compound | 015r0.25 | 43 | 14 | there
[Irpiraciostrabin compound | O1xo4 | 74 | 6th | 115 |
Table 4: Synergistic interactions of compound | and other fungicides in tests] of 1DP PUCCRT
CEEE Taxappm | DCobs | DCexp | gismo | Ixprotioconazole Compound [0.15 + 0.2 78 = —oil - = 1111 | | Hrprocloraz Compound - Jo15: +045 os = —— jen - == / 135 | Table 5: Synergistic interactions of compound |! and other fungicides in tests1DPSEPTTR% dej% of Rate DC DC Ca 5 EE factor e: “+ [ipraciostrobin compound Josssoijão - fer j1a2 - | : [Compound Iiproioraz - - [o46x6 [55 156 [152 Table 6: Synergistic interactions of compound | and other fungicides from 3DC SEPTTR tests a] E AND DC DC Taxappm factor | obs exp | synergism [Lizazaxisirabin compound - [1,3954225] 98 | 72 | 136 | [Iixpiraciostobin compound —jo15x026] 96 | so | 189 | [Mboscaid compound | 04551 | 60 | 22 | 278 [Iizciorotalonta Compound - [045518 | if | 16 | 322 |
Table 7: Synergistic interactions of compound Ill and other fungicides in 1DP tests SEPTTR E fee I / O AND DC DC Taxappm factor | obs exp | synergism [Iisprothioconazole compound - 1.35H1.8 | s8 | so | 109 | [Compound iitpentoprad - | 135 + 18 | o5 [8 | 1o7 | :: - [compostoliprocaraz - [13505] 8 [or | 107: [Compound ii = cioratatonia - | 136754 | 96. | 86 | 111 | Table 8: Synergistic interactions of compound Ill and other fungicides in tests of 3DCSEPTTR eeE E E DC DC Rate factor ppm | obs exp synergism [Compound iirepoxicanazol - fossa.08 [75 160 127 [Compound Ispentopirad - [bones for fes [nat
Table 9: Synergistic interactions of compound IV and other fungicides in 1DP SEPTTR Po Trsagon tests [hollow] [smeaemo | Ppm rate | obs DC exp | synergism [Compound Vsprotoconazole - 42:56. [oo - [78 [118 | [Vscloratalonta compound - [42768 [84 form [128 | Table 10: Synergistic interactions of compound IV and other fungicides in 3DC SEPTTR E roggm tests | D6ole | D6 hey sraeno | . Ppm rate | DC obs | DC exp | synergy Soo [eomposovamoona [a256 | o | 6 | 152 | OO [composoViarodstasmh | 427 | 6 | & | 10 | [Vipradiostobin compound - | 67015 | 7 | 62 | 156 | [Vspentopiad compound - | 42556 | 8 | 81 | 121 | [Vspentoprad compound - | 136818] 74 | 15 | 486 | [Vsboscaid compound - | 18688 | 65 | 52 | 125 | [Compound vcioratalanta - [games | 7 | 10 | 705 | Table 11: Synergistic interactions of compound V and other fungicides in 1DP SEPTTR tests Wow factor Pro | Ppm rate obs exp mo [Compound Vspraciostrobim [260.7 - | o & | 93 | 107 | [Viboscaid compound - [2% - | && | & | 109)
Table 12: Synergistic interactions of compound V and other fungicides in tests: 3DC SEPTTR% tests | %in
CEEE Taxappm | obs exp synergism [Compound Vreponicanazol - | 2x003 | 6t | 48 | 1 [Vspiraciosrabin Compound - | 2x0.15 | 86 | 38 | 230 | : * [Viprodoraz compound - [bonea5 | 50 [to | 26 -: For all tables,% CD =% disease control s

权利要求:
Claims (12)
[1]
CLAIMS 7 1. Synergistic fungicidal mixture comprising the fun- gictically effective of a compound of the formula | -V and at least one fungicide selected from the group consisting of epoxiconazole, protioconazole, azoxistrobin, piraclostrobin, pentiopirad, isopyrazam, bixafen, boscalid, prochloraz and chlorotalonil. A o Da EA x 4 ASIA o o o! yu m. - Fa | CEA 2. pg Ne ÔÕ “” s * "PCR
NV MÁ
[2]
Mixture according to claim 1, wherein the weight ratio of the compound | -V to epoxiconazole is between about 1:10 and about 10: 1.
[3]
Mixture according to claim 1, wherein the weight ratio of compound | -V to protioconazole is between about 1:10 and about 10: 1.
[4]
Mixture according to claim 1, wherein the weight ratio of the compound | -V to azoxystrobin is between about 1:10 and about
101.
[5]
Mixture according to claim 1, wherein the weight ratio of the compound | -V to pyraclostrobin is between about 1:10 and about 10: 1.
[6]
Mixture according to claim 1, wherein the weight ratio of the compound | -V to pentiopirad is between about 1:10 and about 10: 1.
[7]
Mixture according to claim 1, wherein the ratio of "compound weight | to isopyrazam is between about 1:10 and about 10: 1.
[8]
Mixture according to claim 1, wherein the weight ratio of the compound | for bixafen it is between about 1:10 and about 10: 1.
[9]
Mixture according to claim 1, wherein the weight ratio of compound | -V to boscalid is between about 1:10 and about 10: 1.
[10]
Mixture according to claim 1, wherein the weight ratio of compound | -V to prochloraz is between about 1:10 and about 10: 1.
[11]
Mixture according to claim 1, wherein the ratio of compound time | -V to chlorothalonil is between about 1:50 and about 1: 1. -
[12]
12. Fungal composition comprising the fungistically effective amount of the fungal mixture as defined in claim 1 and an agriculturally acceptable vehicle or auxiliary.

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引用文献:

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

US4051173A|1974-04-02|1977-09-27|Merck Patent Gesellschaft Mit Beschrankter Haftung|Phenoxyalkanol derivatives|

EP0612754B1|1993-02-25|1998-08-19|Th. Goldschmidt AG|Organopolysiloxanes with polyether sidechains and their use as hydrolytically stable wetting agent in aqueous systems|

IL123393A|1997-03-03|2004-06-20|Rohm & Haas|Pesticide compositions comprising redispersible polymers|

WO1999011127A1|1997-08-29|1999-03-11|Meiji Seika Kaisha, Ltd.|Rice blast control agent and wheat scab control agent|

TW491686B|1997-12-18|2002-06-21|Basf Ag|Fungicidal mixtures based on amide compounds and tetrachloroisophthalonitrile|

ES2272049T3|1998-02-06|2007-04-16|Meiji Seika Kaisha, Ltd.|NEW ANTIFUNGIC COMPOUND AND PROCEDURE FOR OBTAINING.|

US7183278B1|1998-11-04|2007-02-27|Meiji Seika Kaisha, Ltd.|Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component|

CA2376275A1|1999-08-20|2001-03-01|Michael John Ricks|Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation|

US20030018052A1|1999-07-20|2003-01-23|Ricks Michael J.|Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation|

US6355660B1|1999-07-20|2002-03-12|Dow Agrosciences Llc|Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation|

EP1516875A1|1999-07-20|2005-03-23|Dow AgroSciences LLC|Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation|

KR100743262B1|1999-07-20|2007-07-27|다우 아그로사이언시즈 엘엘씨|Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation|

EP1218368B1|1999-08-20|2007-05-23|Fred Hutchinson Cancer Research Center|COMPOSITIONS AND METHODS FOR MODULATING APOPTOSIS IN CELLS OVER-EXPRESSING bcl-2 FAMILY MEMBER PROTEINS|

US20050239873A1|1999-08-20|2005-10-27|Fred Hutchinson Cancer Research Center|2 Methoxy antimycin a derivatives and methods of use|

FR2803592A1|2000-01-06|2001-07-13|Aventis Cropscience Sa|NOVEL DERIVATIVES OF 3-HYDROXYPICOLINIC ACID, PROCESS FOR THEIR PREPARATION AND FUNGICIDAL COMPOSITIONS CONTAINING SAME|

US20020119979A1|2000-10-17|2002-08-29|Degenhardt Charles Raymond|Acyclic compounds and methods for treating multidrug resistance|

EP1275653A1|2001-07-10|2003-01-15|Bayer CropScience S.A.|Oxazolopyridines and their use as fungicides|

HU0600298A3|2001-07-31|2007-03-28|Dow Agrosciences Llc|Reductive cleavage of the exocyclic ester of uk-2a or its derivatives and products formed therefrom|

AU2002341989A1|2001-10-05|2003-04-22|Dow Agrosciences Llc|Process to produce derivatives from uk-2a derivatives|

AR037328A1|2001-10-23|2004-11-03|Dow Agrosciences Llc|COMPOSITE OF [7-BENCIL-2,6-DIOXO-1,5-DIOXONAN-3-IL] -4-METOXIPIRIDIN-2-CARBOXAMIDE, COMPOSITION THAT UNDERSTANDS AND METHOD THAT USES IT|

AU2004243478A1|2003-05-28|2004-12-09|Basf Aktiengesellschaft|Fungicidal mixtures for controlling rice pathogens|

CN1794914A|2003-05-28|2006-06-28|巴斯福股份公司|Fungicidal mixtures for controlling rice pathogens|

DE10347090A1|2003-10-10|2005-05-04|Bayer Cropscience Ag|Synergistic fungicidal drug combinations|

UA84733C2|2004-02-04|2008-11-25|Янссен Фармацевтика Н.В.|Composition for ensuring synergic antifungal effect, using thereof, a method for obtaining and a product comprising thereof|

GB0419694D0|2004-09-06|2004-10-06|Givaudan Sa|Anti-bacterial compounds|

CA2752117A1|2005-04-18|2006-10-26|Basf Aktiengesellschaft|Preparation containing at least one conazole fungicide a further fungicide and a stabilising copolymer|

US20070010401A1|2005-06-21|2007-01-11|Cheminova A/S|Synergistic combination of a glyphosate herbicide and a triazole fungicide|

CN103947644A|2005-08-05|2014-07-30|巴斯夫欧洲公司|Fungicidal mixtures containing substituted 1-methyl pyrazol-4-yl carboxylic acid anilides|

US8008231B2|2005-10-13|2011-08-30|Momentive Performance Materials Inc.|Extreme environment surfactant compositions comprising hydrolysis resistant organomodified disiloxane surfactants|

WO2008105964A1|2007-02-26|2008-09-04|Stepan Company|Adjuvants for agricultural applications|

CN101808521A|2007-09-26|2010-08-18|巴斯夫欧洲公司|ternary fungicidal compositions comprising boscalid and chlorothalonil|

CN102111999B|2008-05-30|2016-03-16|陶氏益农公司|The method of control QoI refractory fungal pathogene|

AR075899A1|2009-03-20|2011-05-04|Onyx Therapeutics Inc|PROTEASA INHIBITING CRYSTALLINE EPOXYCETON TRIPEPTIDES|

JP5759991B2|2009-08-07|2015-08-05|ダウアグロサイエンシィズエルエルシー|5-Fluoropyrimidinone derivatives|

AU2010279411B2|2009-08-07|2014-10-23|Adama Makhteshim Ltd.|N1-sulfonyl-5-fluoropyrimidinone derivatives|

BR112012004722A2|2009-09-01|2015-09-08|Dow Agrosciences Llc|synergistic fungicidal composition containing a 5-fluoropyrimidine derivative for cereal fungal control|

US20110070278A1|2009-09-22|2011-03-24|Humberto Benito Lopez|Metconazole compositions and methods of use|

ES2688230T3|2009-10-06|2018-10-31|Dow Agrosciences Llc|Stable oil-in-water emulsions|

NZ625074A|2009-10-07|2015-11-27|Dow Agrosciences Llc|Synergistic fungicidal mixtures for fungal control in cereals|

RU2012118395A|2009-10-07|2013-11-20|ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи|SYNERGIC FUNGICIDAL COMPOSITION CONTAINING 5-FLUORCYTOSINE FOR THE STRUGGLE AGAINST FUNGAL DISEASES OF GRAIN CROPS|

EA022245B1|2009-12-08|2015-11-30|Басф Се|Pesticidal mixtures|

PT2563771E|2010-04-24|2016-03-31|Viamet Pharmaceuticals Inc|Metalloenzyme inhibitor compounds|

US8586550B2|2010-06-18|2013-11-19|Green Cross Corporation|Thiazole derivatives as SGLT2 inhibitors and pharmaceutical composition comprising same|

CA2806011A1|2010-08-03|2012-02-09|Basf Se|Fungicidal compositions|

WO2012018885A1|2010-08-05|2012-02-09|Dow Agrosciences Llc|Pesticide compositions of meso-sized particles with enhanced activity|

CN104285962A|2010-08-05|2015-01-21|拜耳知识产权有限责任公司|Active compounds combinations comprising prothioconazole and fluxapyroxad|

JP2012036143A|2010-08-10|2012-02-23|Sumitomo Chemical Co Ltd|Plant disease control composition and application for same|

AU2011333311A1|2010-11-24|2013-07-04|Stemergie Biotechnology Sa|Inhibitors of the activity of Complex III of the mitochondrial electron transport chain and use thereof for treating diseases|

JP6013032B2|2011-07-08|2016-10-25|石原産業株式会社|Disinfectant composition and method for controlling plant diseases|

US9414596B2|2012-01-20|2016-08-16|Viamet Pharmaceuticals, Inc.|Metalloenzyme inhibitor compounds|

RU2014149201A|2012-05-07|2016-06-27|ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи|MACROCYCLIC PICOLINAMIDES AS FUNGICIDES|

MX343981B|2012-05-07|2016-12-01|Dow Agrosciences Llc|Use of pro-fungicides of uk-2a for control of black sigatoka.|

DK2847185T3|2012-05-07|2017-02-20|Dow Agrosciences Llc|Macrocyclic picolinamides as fungicides|

CA2872022A1|2012-05-07|2013-11-14|Dow Agrosciences Llc|Use of pro-fungicides of uk-2a for control of soybean rust|

EP2847188B1|2012-05-07|2016-12-21|Dow AgroSciences LLC|Macrocyclic picolinamides as fungicides|

ES2666144T3|2012-12-28|2018-05-03|Dow Agrosciences Llc|Synergistic fungicidal mixtures for fungal control in cereals|

KR20150103175A|2012-12-31|2015-09-09|다우 아그로사이언시즈 엘엘씨|Macrocyclic picolinamides as fungicides|

US9750248B2|2012-12-31|2017-09-05|Dow Agrosciences Llc|Synergistic fungicidal compositions|

BR112016006874A2|2013-10-01|2017-08-01|Dow Agrosciences Llc|use of macrocyclic picolinamides as fungicides|

EP3086642A4|2013-12-26|2017-09-27|Dow Agrosciences LLC|Use of macrocyclic picolinamides as fungicides|

CN106061259B|2013-12-31|2019-08-16|美国陶氏益农公司|Synergistic fungicidal mixture for fungus control in cereal|BR112012004722A2|2009-09-01|2015-09-08|Dow Agrosciences Llc|synergistic fungicidal composition containing a 5-fluoropyrimidine derivative for cereal fungal control|

RU2012118395A|2009-10-07|2013-11-20|ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи|SYNERGIC FUNGICIDAL COMPOSITION CONTAINING 5-FLUORCYTOSINE FOR THE STRUGGLE AGAINST FUNGAL DISEASES OF GRAIN CROPS|

NZ625074A|2009-10-07|2015-11-27|Dow Agrosciences Llc|Synergistic fungicidal mixtures for fungal control in cereals|

DK2847185T3|2012-05-07|2017-02-20|Dow Agrosciences Llc|Macrocyclic picolinamides as fungicides|

RU2014149201A|2012-05-07|2016-06-27|ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи|MACROCYCLIC PICOLINAMIDES AS FUNGICIDES|

MX343981B|2012-05-07|2016-12-01|Dow Agrosciences Llc|Use of pro-fungicides of uk-2a for control of black sigatoka.|

EP2847188B1|2012-05-07|2016-12-21|Dow AgroSciences LLC|Macrocyclic picolinamides as fungicides|

CA2872022A1|2012-05-07|2013-11-14|Dow Agrosciences Llc|Use of pro-fungicides of uk-2a for control of soybean rust|

PL2864293T3|2012-06-22|2016-12-30|Fungicidal 4-methylanilino pyrazoles|

ES2666144T3|2012-12-28|2018-05-03|Dow Agrosciences Llc|Synergistic fungicidal mixtures for fungal control in cereals|

KR20150103175A|2012-12-31|2015-09-09|다우 아그로사이언시즈 엘엘씨|Macrocyclic picolinamides as fungicides|

US9482661B2|2012-12-31|2016-11-01|Dow Agrosciences Llc|Synthesis and use of isotopically labeled macrocyclic compounds|

US10455835B2|2012-12-31|2019-10-29|Dow Agrosciences Llc|Fungicidal compositions for controlling leaf spots in sugar beets|

US9247742B2|2012-12-31|2016-02-02|Dow Agrosciences Llc|Synergistic fungicidal compositions|

US9750248B2|2012-12-31|2017-09-05|Dow Agrosciences Llc|Synergistic fungicidal compositions|

WO2014130409A2|2013-02-21|2014-08-28|E. I. Du Pont De Nemours And Company|Fungicidal pyrazole mixtures|

CN103988840A|2013-03-20|2014-08-20|海南正业中农高科股份有限公司|Fungicidal composition containing penthiopyrad and prochloraz|

AU2014254261B2|2013-04-15|2017-11-09|Fmc Corporation|Fungicidal amides|

PL2986601T3|2013-04-15|2017-10-31|Fmc Corp|Fungicidal carboxamides|

JP6539205B2|2013-07-10|2019-07-03|ＭｅｉｊｉＳｅｉｋａファルマ株式会社|Composition for controlling synergistic plant diseases comprising picolinic acid derivative|

BR112016006874A2|2013-10-01|2017-08-01|Dow Agrosciences Llc|use of macrocyclic picolinamides as fungicides|

WO2015050818A1|2013-10-01|2015-04-09|Dow Agrosciences Llc|Macrocyclic picolinamide compounds with fungicidal activity|

US9549556B2|2013-12-26|2017-01-24|Dow Agrosciences Llc|Macrocyclic picolinamides as fungicides|

EP3086642A4|2013-12-26|2017-09-27|Dow Agrosciences LLC|Use of macrocyclic picolinamides as fungicides|

CN106061259B|2013-12-31|2019-08-16|美国陶氏益农公司|Synergistic fungicidal mixture for fungus control in cereal|

US9532570B2|2013-12-31|2017-01-03|Adama Makhteshim Ltd.|Synergistic fungicidal mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one for fungal control in cereals|

GB201401117D0|2014-01-23|2014-03-12|Univ Sussex The|Antifungal composition|

WO2015123193A1|2014-02-12|2015-08-20|E. I. Du Pont De Nemours And Company|Fungicidal benzodipyrazoles|

WO2015157005A1|2014-04-10|2015-10-15|E I Du Pont De Nemours And Company|Substituted tolyl fungicide mixtures|

EP3140289A1|2014-05-06|2017-03-15|E. I. du Pont de Nemours and Company|Fungicidal pyrazoles|

WO2015171408A1|2014-05-06|2015-11-12|Dow Agrosciences Llc|Macrocyclic picolinamides as fungicides|

EP3166936A4|2014-07-08|2017-11-22|Dow AgroSciences LLC|Macrocyclic picolinamides as fungicides|

US9686984B2|2014-07-08|2017-06-27|Dow Agrosciences Llc|Macrocyclic picolinamides as fungicides|

PL3166927T3|2014-07-08|2020-10-19|Dow Agrosciences Llc|Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids|

MX2016017124A|2014-07-08|2017-05-10|Dow Agrosciences Llc|Process for the preparation of 3-hydroxypicolinic acids.|

US20160037774A1|2014-08-08|2016-02-11|Dow Agrosciences Llc|Synergistic fungicidal mixtures for fungal control in cereals|

MX2017008441A|2014-12-30|2018-04-20|Dow Agrosciences Llc|Use of picolinamide compounds with fungicidal activity.|

MX2017008442A|2014-12-30|2017-10-02|Dow Agrosciences Llc|Use of picolinamides as fungicides.|

EP3808181A1|2014-12-30|2021-04-21|Dow AgroSciences LLC|Use of picolinamide compounds as fungicides|

EP3240415A4|2014-12-30|2018-06-13|Dow AgroSciences LLC|Fungicidal compositions|

NZ732573A|2014-12-30|2019-01-25|Dow Agrosciences Llc|Use of picolinamide compounds with fungicidal activity|

US10173971B2|2014-12-30|2019-01-08|Dow Agrosciences Llc|Picolinamides with fungicidal activity|

EP3271336A1|2015-03-19|2018-01-24|E. I. du Pont de Nemours and Company|Fungicidal pyrazoles|

EP3141118A1|2015-09-14|2017-03-15|Bayer CropScience AG|Compound combination for controlling control phytopathogenic harmful fungi|

BR112018013434A2|2015-12-30|2018-12-04|Dow Agrosciences Llc|fungal control of white mold|

WO2017194363A1|2016-05-10|2017-11-16|Bayer Cropscience Aktiengesellschaft|Compound combination for controlling phytopathogenic harmful fungi|

EP3245872A1|2016-05-20|2017-11-22|BASF Agro B.V.|Pesticidal compositions|

CN109843877A|2016-08-26|2019-06-04|美国陶氏益农公司|The purposes of fungicide prevention and treatment rice blast before UK-2A|

US20180055049A1|2016-08-26|2018-03-01|Dow Agrosciences Llc|Use of pro-fungicides of uk-2a for control of brown rot diesease on stone and pome fruits|

US10173982B2|2016-08-30|2019-01-08|Dow Agrosciences Llc|Picolinamides as fungicides|

US10034477B2|2016-08-30|2018-07-31|Dow Agrosciences Llc|Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity|

US10111432B2|2016-08-30|2018-10-30|Dow Agrosciences Llc|Picolinamide N-oxide compounds with fungicidal activity|

WO2018044987A1|2016-08-30|2018-03-08|Dow Agrosciences Llc|Thiopicolinamide compounds with fungicidal activity|

EP3558984A1|2016-12-20|2019-10-30|FMC Corporation|Fungicidal oxadiazoles|

BR102018000132A2|2017-01-05|2018-08-14|Dow Agrosciences Llc|picolinamides as fungicides|

CR20190405A|2017-03-07|2019-10-18|Upl Ltd|Fungicidal combinations|

TW201904950A|2017-04-06|2019-02-01|美商富曼西公司|Fungicidal oxadiazoles|

TW201842851A|2017-05-02|2018-12-16|美商陶氏農業科學公司|Synergistic mixtures for fungal control in cereals|

TW201842848A|2017-05-02|2018-12-16|美商陶氏農業科學公司|Synergistic mixtures for fungal control in vegetables|

TW201842849A|2017-05-02|2018-12-16|美商陶氏農業科學公司|Synergistic mixtures for fungal control in cereals|

CA3062074A1|2017-05-02|2018-11-08|Dow Agrosciences Llc|Use of an acyclic picolinamide compound as a fungicide for fungal diseases on turfgrasses|

AR112221A1|2017-07-05|2019-10-02|Fmc Corp|FUNGICIDE OXADIAZOLES, COMPOSITION THAT INCLUDE THEM AND A METHOD TO CONTROL PHYTO DISEASES THAT USE THEM|

WO2019101580A1|2017-11-21|2019-05-31|Syngenta Participations Ag|Fungicidal compositions|

RU2672493C1|2018-02-14|2018-11-15|ООО "Агро Эксперт Груп"|Fungicidal composition |

RU2661392C1|2018-02-14|2018-07-16|Общество с ограниченной ответственностью "Агро Эксперт Груп"|Fungicidal composition |

BR102019004480A2|2018-03-08|2019-10-01|Dow Agrosciences Llc|PICOLINAMIDES AS FUNGICIDES|

TW202010738A|2018-09-06|2020-03-16|美商富曼西公司|Fungicidal nitroanilino substituted pyrazoles|

PE20211706A1|2018-09-14|2021-09-01|Fmc Corp|HYDRATES AND FUNGICIDAL HALOMETHYL KETONES|

TW202026284A|2018-11-06|2020-07-16|美商富曼西公司|Substituted tolyl fungicides|

WO2021146522A1|2020-01-15|2021-07-22|Fmc Corporation|Fungicidal amides|

UY39082A|2020-02-14|2021-09-30|Fmc Corp|PYRIDAZINONES FUNGICIDES|

RU2763596C1|2021-07-19|2021-12-30|Акционерное общество "Щелково Агрохим"|Fungicidal synergistic combination of biologically active substances|

法律状态:
2020-09-08| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|

2020-12-15| B07A| Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]|

2021-03-23| B09B| Patent application refused [chapter 9.2 patent gazette]|

2021-06-01| B09B| Patent application refused [chapter 9.2 patent gazette]|Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |

2021-11-23| B350| Update of information on the portal [chapter 15.35 patent gazette]|

优先权:

申请号 | 申请日 | 专利标题

US24947909P| true| 2009-10-07|2009-10-07|

US61/249,479|2009-10-07|

PCT/US2010/051598|WO2011044213A1|2009-10-07|2010-10-06|Synergistic fungicidal mixtures for fungal control in cereals|

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